To Process or to Decay: A Mechanistic View of the Nuclear RNA Exosome. Lingaraju M, Schuller JM, Falk S, Gerlach P, Bonneau F, Basquin J, Benda C, Conti E. Cold Spring Harb Symp Quant Biol. 2020 Jun 3:040295. doi: 10.1101/sqb.2019.84.040295.

InsP6 binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex. Gat Y*, Schuller JM*, Lingaraju M, Weyher E, Bonneau F, Strauss M, Murray PJ, Conti E. NSMB. 2019 Dec;26(12):1089-1093. doi: 10.1038/s41594-019-0342-7.

Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase Schäfer IB, Yamashita M, Schuller JM, Schüssler S, Strauss M, Conti E. Cell. 2019 May 30;177(6):1619-1631.e21, doi: 10.1016/j.cell.2019.04.013.

Distinct and evolutionary conserved structural features of the human nuclear exosome complex. Gerlach P.*, Schuller JM*, Bonneau F, Basquin J, Reichelt P, Falk S, Conti E. Elife. 2018 Jul 26;7, doi: 10.7554/eLife.38686.

Structure of the nuclear exosome captured on a maturing preribosome. Schuller JM*, Falk S*, Fromm L, Hurt E, Conti E. Science. 2018 Apr 13;360(6385):219-222. 10.1126/science.aar5428.

Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome. Fromm L, Falk S, Flemming D, Schuller JM, Thoms M, Conti E, Hurt E. Nat Commun. 2017 Nov 27;8(1):1787. doi: 10.1038/s41467-017-01786-9.

Conformational changes of the AAA+ ATPase p97 revisited Schuller JM, Beck F, Lössl P,Heck AJ, Förster F. FEBS Lett. 2016 Mar;590(5):595-604, doi: 10.1002/1873-3468.12091.

Structural basis for recognition and remodeling of the TBP:DNA:NC2 complex by Mot1. Butryn A, Schuller JM, Stoehr G, Runge-Wollmann P, Förster F, Auble DT, Hopfner KP. eLife. 2016 Mar 10;4, doi: 10.7554/eLife.07432.

Effect of lipid head groups on double-layered two-dimensional crystals formed by aquaporin-0 Hite RK, Chiu PL, Schuller JM, Walz T. Plos One. 2015 Jan 30;10(1):e0117371, doi: 10.1371/journal.pone.0117371.

Molecular architecture of the HerA-NurA DNA double-strand break resection complex. Byrne RT*, Schuller JM*, Unverdorben P, Förster F, Hopfner KP. FEBS Letters 11/2014 doi: 10.1016/j.febslet.2014.10.035.

Emerging mechanistic insights into AAA complexes regulating proteasomal degradation. Förster F, Schuller JM, Unverdorben P, Aufderheide A. Biomolecules. 2014 Aug 6;4(3):774-94. doi: 10.3390/biom4030774.

Fast and accurate reference-free alignment of subtomograms. Chen Y, Pfeffer S, Hrabe T, Schuller JM, Förster F. J Struct Biol. 2013 Jun;182(3):235-45. doi: 10.1016/j.jsb.2013.03.002. Epub 2013 Mar 22.

Structure and catalytic mechanism of a cyclic dipeptide prenyltransferase with broad substrate promiscuity. Schuller JM*, Zocher G*, Liebhold M, Xie X, Stahl M, Li SM, Stehle T. J Mol Biol. 06/2012; 422(1):87-99., doi: 10.1016/j.jmb.2012.05.033.

SYNMIKRO Young Researchers Groups

Almost all scientific members of SYNMIKRO are actively involved in DFG’s Collaborative Research Centers (Sonderforschungsbereiche), Research Training Groups (Graduiertenkollegs), or other Cooperative Research projects. Alongside performing adventurous experiments, and reporting excellent science, SYNMIKRO substantially promotes potential Young Research Group Leaders by constantly keeping its doors open to welcome and support Young Researchers planning to set up an Independent Research Group.
Our Young Research Groups