Lotte Søgaard-Andersen

Lotte Søgaard-Andersen

Prof. Dr. Lotte Søgaard-Andersen

Max Planck Institute for Terrestrial Microbiology
Karl-von-Frisch-Straße 10, 35043 Marburg
+49-6421 178 201


Research area

The overall goal of our research is to unravel the mechanisms that allow bacteria to adapt and differentiate in response to changes in the environment. Bacteria have evolved several strategies that allow them to cope with such changes including changes in gene expression ranging from changes in the expression of relatively few genes to changes in the expression of large numbers of genes culminating in cell differentiation, changes in the motility behavior of cells, and changes to the cell cycle. To implement these strategies bacterial cells have to process vast amounts of information and then generate the appropriate output response(s). Information processing is carried out by complex networks of signal transduction proteins. We try to understand how these networks are organized in space and time to allow the ordered execution of various tasks.


Molecular microbiology

Cellular microbiology

Bacterial motility

Bacterial cell cycle

Bacterial signal transduction

Recent Publications

1. Szadkowski, D, Harms, A, Carreira, LAM, Wigbers, M, Potapova, A, Wuichet, K, Keilberg, D, Gerland, U, Søgaard-Andersen, L (2019). Spatial control of the GTPase MglA by localized RomR-RomX GEF and MglB GAP activities enables Myxococcus xanthus motility. Nat Microbiol 4: 1344-1355

2. Gómez-Santos, N, Glatter, T, Koebnik, R, Świątek-Połatyńska, MA, Søgaard-Andersen, L. (2019) A TonB-dependent transporter is required for secretion of protease PopC across the bacterial outer membrane. Nat Commun 10: 1360

3. Schumacher, D, Bergeler, S, Harms, A, Vonck, J, Huneke-Voigt, S, Frey, E, Søgaard-Andersen, L (2017) The PomXYZ proteins self-organize on the bacterial nucleoid to stimulate cell division. Dev Cell 41: 299-314.e13

SYNMIKRO Young Researchers Groups

Almost all scientific members of SYNMIKRO are actively involved in DFG’s Collaborative Research Centers (Sonderforschungsbereiche), Research Training Groups (Graduiertenkollegs), or other Cooperative Research projects. Alongside performing adventurous experiments, and reporting excellent science, SYNMIKRO substantially promotes potential Young Research Group Leaders by constantly keeping its doors open to welcome and support Young Researchers planning to set up an Independent Research Group.
Our Young Research Groups